The effects of adjunctive topiramate on cognitive function in patients with epilepsy.

  title={The effects of adjunctive topiramate on cognitive function in patients with epilepsy.},
  author={Suzee Lee and V. Sziklas and Frederick Andermann and S. Farnham and Gail R. Risse and Mary C. Gustafson and John M. Gates and Patricia E. Penovich and Abdullah Al-Asmi and François Dubeau and M. Jones-Gotman},
  volume={44 3},
PURPOSE We investigated possible cognitive effects of topiramate (TPM) in polypharmacy on patients with intractable epilepsy. METHODS Study 1 evaluated 22 consecutively admitted patients whose antiepileptic drugs (AEDs) on admission to the Montreal Neurological Hospital included TPM. Performance on neuropsychological tests administered on and subsequently off TPM was analyzed. Four patients also were tested before taking TPM, allowing comparisons off, then on, and then off the drug again… CONTINUE READING

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