The effects of adiponectin and leptin on changes in bone mineral density

  title={The effects of adiponectin and leptin on changes in bone mineral density},
  author={Kamil E. Barbour and Joseph M. Zmuda and Robert Boudreau and Elsa S. Strotmeyer and Mara J. Horwitz and Rhobert Wyn Evans and Alka M Kanaya and T. B. Harris and Jane A. Cauley},
  journal={Osteoporosis International},
We tested the hypothesis that low leptin and high adiponectin levels are associated with higher rates of bone mineral density (BMD) loss among 3,075 men and women, aged 70–79, from the Health Aging and Body Composition Study. Results suggest that adiponectin, but not leptin, is a risk factor for bone loss in women. Adiponectin and leptin are hormones secreted by adipose cells that may impact BMD. Few studies have evaluated the longitudinal association of leptin and adiponectin levels with rates… CONTINUE READING
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