The effects of acquisition training schedule on extinction and reinstatement of cocaine self-administration in male rats.

@article{Valles2006TheEO,
  title={The effects of acquisition training schedule on extinction and reinstatement of cocaine self-administration in male rats.},
  author={Rodrigo Valles and Ang{\'e}lica Lacerda Rocha and Jack R. Nation},
  journal={Experimental and clinical psychopharmacology},
  year={2006},
  volume={14 2},
  pages={245-53}
}
Partial reinforcement is known to increase resistance to extinction (Rn) relative to training with continuous reinforcement. This phenomenon, referred to as the partial reinforcement extinction effect, is one of the most robust in learning and conditioning studies. Experiment 1 investigated manipulations known to affect the partial reinforcement extinction effect and determined their possible relevance for drug use patterns. Male rats received intravenous cocaine self-administration training… CONTINUE READING