The effects of a duplication in the ovine growth hormone (GH) gene on GH expression in the pituitaries of ram lambs from lean and fat-selected sheep lines.

@article{Fleming1997TheEO,
  title={The effects of a duplication in the ovine growth hormone (GH) gene on GH expression in the pituitaries of ram lambs from lean and fat-selected sheep lines.},
  author={J. G. S. Fleming and James M. Suttie and Grant W. Montgomery and Jinny Gunn and Shannon K Stuart and Roger P. Littlejohn and Elisha Gootwine},
  journal={Domestic animal endocrinology},
  year={1997},
  volume={14 1},
  pages={17-24}
}
Growth hormone (GH) gene expression was investigated in pituitaries of 14- to 15-month-old ram lambs from flocks selected for high (fat) or low (lean) back fat depth, which were also homozygous for a single GH gene allele, heterozygous or homozygous for a duplication in the GH gene. The pituitaries of lean sheep of all three GH genotypes were significantly heavier than those of fat sheep, but there were no pituitary weight differences between GH genotypes. No significant lean-fat selection line… CONTINUE READING