The effects of a cholinesterase inhibitor are prominent in patients with fluctuating cognition: a part 3 study of the main mechanism of cholinesterase inhibitors in dementia.

@article{Onofrj2003TheEO,
  title={The effects of a cholinesterase inhibitor are prominent in patients with fluctuating cognition: a part 3 study of the main mechanism of cholinesterase inhibitors in dementia.},
  author={Marco Onofrj and Astrid Thomas and Diego Iacono and Anna Lisa Luciano and Angelo Di Iorio},
  journal={Clinical neuropharmacology},
  year={2003},
  volume={26 5},
  pages={
          239-51
        }
}
Fluctuating cognition is evidenced in different forms of dementia and is accompanied by electroencephalographic (EEG) abnormalities. The authors hypothesize that cholinesterase inhibitors are effective mostly in patients with fluctuating cognition. Twenty-three patients affected by mild dementia with similar scores on Mini-Mental State Examination (MMSE), Alzheimer Disease Assessment Scale-cognitive subscale (ADAS-cog), and Unified Parkinson's Disease Rating Scale evaluation were classified in… CONTINUE READING
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