The effects of a D1 and a D2 dopamine antagonist on behavior maintained by cocaine or food

@article{Woolverton1989TheEO,
  title={The effects of a D1 and a D2 dopamine antagonist on behavior maintained by cocaine or food},
  author={W. Woolverton and R. M. Virus},
  journal={Pharmacology Biochemistry and Behavior},
  year={1989},
  volume={32},
  pages={691-697}
}
  • W. Woolverton, R. M. Virus
  • Published 1989
  • Psychology, Medicine
  • Pharmacology Biochemistry and Behavior
  • The purpose of the present experiment was to determine whether a D1 or a D2 dopamine antagonist could alter responding maintained by cocaine at doses that did not affect responding maintained by food. Rhesus monkeys were trained to press a lever in daily experimental sessions under a 3 component multiple schedule of reinforcement. In the first and third components, food was available under a fixed-ratio 30/time-out 2 min (FR30/TO 2) schedule. In the second component, cocaine was available under… CONTINUE READING
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    References

    SHOWING 1-10 OF 13 REFERENCES
    Fixed-interval schedule of cocaine reinforcement: effect of dose and infusion duration.
    • 286
    A choice procedure for drug reinforcers: cocaine and methylphenidate in the rhesus monkey.
    • 240
    Naltrexone effects on food-and codeine-maintained responding in rhesus monkeys.
    • S. Herling
    • Psychology, Medicine
    • European journal of pharmacology
    • 1981
    • 15
    • PDF
    Intravenous self-administration of dopamine receptor agonists by rhesus monkeys.
    • 202
    Antagonism of the amphetamine cue by both classical and atypical antipsychotic drugs.
    • 105