The effects of TSH receptor antibodies on protein kinase C in the thyroid.

@article{Ginsberg1993TheEO,
  title={The effects of TSH receptor antibodies on protein kinase C in the thyroid.},
  author={Jody Ginsberg and Paul Gerard Murray},
  journal={Clinical endocrinology},
  year={1993},
  volume={38 1},
  pages={45-8}
}
OBJECTIVE There is increasing evidence that TSH activates a non-cyclic-AMP-dependent pathway in the thyroid resulting in protein kinase C activation. We have previously demonstrated that TSH activates protein kinase C by causing translocation of protein kinase C from an inactive cytosolic site to its active membrane-bound form in porcine thyroid cells. In… CONTINUE READING