The effects of PTBP3 silencing on the proliferation and differentiation of MKN45 human gastric cancer cells.

@article{Chen2014TheEO,
  title={The effects of PTBP3 silencing on the proliferation and differentiation of MKN45 human gastric cancer cells.},
  author={Bingguang Chen and Ai-guang Zhao and Jin Shao and Xiao-yan Mu and Lin Jiang and Jian Liu},
  journal={Life sciences},
  year={2014},
  volume={114 1},
  pages={29-35}
}
AIMS PTBP3 overexpression inhibits the differentiation of leukemia cells; however, its effects on the differentiation and proliferation of solid cancer cells remain unclear. Thus, the impact of PTBP3 on the differentiation and proliferation of gastric cancer cells was investigated. MAIN METHODS PTBP3 expression was analyzed in normal and tumor tissues using immunohistochemistry. A xenograft model was established in nude mice by subcutaneous injection of untransfected human gastric cancer… CONTINUE READING

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