The effects of Micro-429 on inhibition of cervical cancer cells through targeting ZEB1 and CRKL.

@article{Wang2016TheEO,
  title={The effects of Micro-429 on inhibition of cervical cancer cells through targeting ZEB1 and CRKL.},
  author={Yanli Wang and Xue Dong and B. Y.-K. Hu and Xiao-Jing Wang and Qian Wang and Wu-Liang Wang},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={2016},
  volume={80},
  pages={311-321}
}
MicroRNA-429 (miR-429) has been suggested to inhibit epithelial-mesenchymal transition (EMT), mainly due to targeting of ZEB1 and ZEB2, which are repressors of the cell to cell contact protein, E-cadherin. In this study, we indicated that regulation of miR-429 in cervical cancer cells modulates cell migration, elongation, as well as transforming growth factor β (TGF-β)-induced stress fiber formation through regulating the cytoskeleton reorganization which is likely independent of the zinc… CONTINUE READING