Corpus ID: 18854569

The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial.

@article{Lyon2011TheEO,
  title={The effects of L-theanine (Suntheanine{\textregistered}) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial.},
  author={Michael R. Lyon and Mahendra Parkash Kapoor and Lekh Raj Juneja},
  journal={Alternative medicine review : a journal of clinical therapeutic},
  year={2011},
  volume={16 4},
  pages={
          348-54
        }
}
INTRODUCTION The purpose of this study was to investigate the efficacy and safety of L-theanine as an aid to the improvement of objectively measured sleep quality in a population of 98 male children formally diagnosed with attention-deficit/hyperactivity disorder (ADHD). METHODS A randomized, double-blind, placebo-controlled trial was conducted involving boys, ages 8-12 years, who had been previously diagnosed with ADHD. An experienced physician confirmed the diagnosis of ADHD in each subject… Expand
The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial.
  • S. Hirayama, K. Terasawa, +5 authors R. Jäger
  • Medicine
  • Journal of human nutrition and dietetics : the official journal of the British Dietetic Association
  • 2014
TLDR
PS supplementation significantly improved ADHD symptoms and short-term auditory memory in children and might be a safe and natural nutritional strategy for improving mental performance in young children suffering from ADHD. Expand
L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
TLDR
This preliminary study did not support the efficacy of L-theanine in the treatment of anxiety symptoms in GAD, and further studies to explore the application of the amino acid in sleep disturbance are warranted. Expand
Effects of l-theanine–caffeine combination on sustained attention and inhibitory control among children with ADHD: a proof-of-concept neuroimaging RCT
We examined the acute effects of l-theanine, caffeine and their combination on sustained attention, inhibitory control and overall cognition in boys with attention deficit hyperactivity disorderExpand
Add-On Pregnenolone with L-Theanine to Antipsychotic Therapy Relieves Negative and Anxiety Symptoms of Schizophrenia: An 8-Week, Randomized, Double-Blind, Placebo-Controlled Trial.
TLDR
Negative symptoms were found to be significantly improved with moderate effect sizes among patients who received PREG-LT, in comparison with the placebo group, and Pregnenolone with L-theanine augmentation may offer a new therapeutic strategy for treatment of negative and anxiety symptoms in schizophrenia and schizoaffective disorder. Expand
Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study
TLDR
It is suggested that chronic (8-week) l-theanine administration is safe and has multiple beneficial effects on depressive symptoms, anxiety, sleep disturbance and cognitive impairments in patients with MDD. Expand
Subjective assessment of the effects of an herbal supplement containing lavender essential oil on sleep quality: A randomized, double-blind, placebo-controlled crossover study
TLDR
The lavender oil containing supplement was effective in improving several subjective sleep parameters in participants with mild to moderate insomnia. Expand
Safety, Tolerability and Efficacy of Drugs for Treating Behavioural Insomnia in Children with Attention-Deficit/Hyperactivity Disorder: A Systematic Review with Methodological Quality Assessment
TLDR
Clonidine, melatonin, L-theanine, eszopiclone and guanfacine were well tolerated with mild to moderate adverse events; zolpidem was associated with neuropsychiatric adverse effects. Expand
Psychotropic effects of L-theanine and its clinical properties: from the management of anxiety and stress to a potential use in schizophrenia.
TLDR
Data suggests that L-theanine administered at daily doses ranging from 200 to 400 mg for up to 8 weeks are safe and induce anxiolytic and anti-stress effects in acute and chronic conditions, and L- theanine at doses lower and higher than these may also show promising therapeutic potential. Expand
Psychotropic effects of L-theanine and its clinical properties: From the management of anxiety and stress to a potential use in schizophrenia.
TLDR
Data suggests that L-theanine administered at daily doses ranging from 200 to 400 mg for up to 8 weeks are safe and induce anxiolytic and anti-stress effects in acute and chronic conditions, and L- theanine at doses lower and higher than these may also show promising therapeutic potential. Expand
To sleep or not to sleep: a systematic review of the literature of pharmacological treatments of insomnia in children and adolescents with attention-deficit/hyperactivity disorder.
TLDR
There is a relative paucity of evidence for the pharmacological treatment of ADHD-related sleep disorders; therefore, further research should be conducted to replicate these findings and obtain reliable results. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 57 REFERENCES
A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study.
TLDR
LGNC-07 improved memory and selective attention by significantly increasing the Rey-Kim memory quotient and word reading in the subjects with MMSE-K scores of 21-23 and has potential as an intervention for cognitive improvement, suggests this study. Expand
Acute impact of immediate release methylphenidate administered three times a day on sleep in children with attention-deficit/hyperactivity disorder.
TLDR
Although the medication was effective in reducing ADHD symptoms, analyses of actigraphy and sleep diary data found statistically and clinically significant changes in the children's total sleep time and sleep onset latency in the medication compared to the no medication conditions. Expand
Actigraphic monitoring during sleep of children with ADHD on methylphenidate and placebo.
TLDR
Investigating the relationship of activity levels during sleep and therapeutic response to methylphenidate suggests that responders to MPH treatment do not experience greater sleep disturbances than nonresponders, at at the dose studied. Expand
The sleep of children with attention deficit hyperactivity disorder on and off methylphenidate: a matched case–control study
TLDR
It is suggested that methylphenidate reduces sleep quantity but does not alter sleep architecture in children diagnosed with ADHD, suggesting an adequate amount of sleep is integral to good daytime functioning, thus the sleep side effects of methylphenidates may affect adversely the daytime symptoms the drug is targeted to control. Expand
Sleep in children with attention-deficit/hyperactivity disorder: meta-analysis of subjective and objective studies.
TLDR
A meta-analysis of subjective and objective sleep studies comparing sleep in children with attention-deficit/hyperactivity disorder (ADHD) versus controls indicated that children with ADHD had significantly higher bedtime resistance and more sleep onset difficulties. Expand
The effects of l-theanine, caffeine and their combination on cognition and mood
TLDR
The results suggest that beverages containing L-theanine and caffeine may have a different pharmacological profile to those containing caffeine alone. Expand
Sleep in children with attention-deficit hyperactivity disorder (ADHD): a review of naturalistic and stimulant intervention studies.
TLDR
The main objectives of this review were to provide pediatric clinicians and researchers a clear and concise summary of published sleep data in children with ADHD, to provide a more accurate description of the current knowledge of the relationship between sleep and ADHD, and to provide current information on the effect of stimulant medication on sleep. Expand
Pharmacotherapy of attention-deficit/hyperactivity disorder: nonstimulant medication approaches
TLDR
This review focuses on etiology, assessment and treatment of ADHD, in particular alternative treatment approaches with various nonstimulant agents, especially atomoxetine. Expand
The acute effects of L‐theanine in comparison with alprazolam on anticipatory anxiety in humans
TLDR
It is suggested that while L‐ theanine may have some relaxing effects under resting conditions, neither L‐theanine not alprazolam demonstrate any acute anxiolytic effects under conditions of increased anxiety in the AA model. Expand
Association between sleep problems and symptoms of attention-deficit/hyperactivity disorder in young adults.
TLDR
Examination of sleep-related problems and symptoms of attention-deficit/hyperactivity disorder in a community sample of young adults in Taiwan showed ADHD symptoms in young adults are related to sleep problems. Expand
...
1
2
3
4
5
...