The effects of HIV-1 Tat protein on cell cycle during cervical carcinogenesis.

Abstract

The role of HPV in the carcinogenesis of intraepithelial and invasive anogenital lesions is currently well established. E6 and E7 oncoproteins of high-risk HPV genotypes are known to inactivate p53 and pRb pathways. Several studies have described an increased prevalence and recurrence of both cervical HPV infection and invasive cervical cancer among HIV-1… (More)

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@article{Nyagol2006TheEO, title={The effects of HIV-1 Tat protein on cell cycle during cervical carcinogenesis.}, author={Joshua Nyagol and Eleonora Leucci and Anna Onnis and Giulia De Falco and Chiara Tigli and Francesca Sanseverino and M Torriccelli and Nazzareno Palummo and Lorenzo Pacenti and Robert Santopietro and D. Spina and Peter B Gichangi and Lucy W Muchiri and Stefano Lazzi and Francesca Petraglia and Leda Leoncini and A. Giordano}, journal={Cancer biology & therapy}, year={2006}, volume={5 6}, pages={684-90} }