The effects of Ginkgo biloba extract on lipopolysaccharide-induced inflammation in vitro and in vivo.

@article{Ilieva2004TheEO,
  title={The effects of Ginkgo biloba extract on lipopolysaccharide-induced inflammation in vitro and in vivo.},
  author={I. Ilieva and K. Ohgami and K. Shiratori and Y. Koyama and Kazuhiko Yoshida and S. Kase and H. Kitamei and Y. Takemoto and K. Yazawa and S. Ohno},
  journal={Experimental eye research},
  year={2004},
  volume={79 2},
  pages={
          181-7
        }
}
PURPOSE Ginkgo biloba extract (GBE) contains many different flavone glycosides and terpenoides. Several previous studies have demonstrated that GBE exhibits a wide variety of biological activities, including an antioxidant action, on which we focused our attention. The aim of the present study was to investigate the efficacy of GBE on endotoxin induced uveitis in rats. The anti-inflammatory potency of GBE in vivo was compared with that of prednisolone. In addition, we also investigated nitric… Expand
ANTI-INFLAMMATORY EFFECTS OF BIDARIA KHANDALENSE EXTRACT ON RAT ENDOTOXIN-INDUCED UVEITIS
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TLDR
Data show that bilobalide is a potent anti-inflammatory and antihyperalgesic agent, the therapeutic effects of which are mediated in part through a central site of action, and may account for the therapeutic action of the whole extract G. biloba. Expand
Antihyperglycemic Effect of Ginkgo biloba Extract in Streptozotocin-Induced Diabetes in Rats
TLDR
GBE possesses antihyperglycemic, antioxidant, and antihyperlipidemia activities in STZ-induced chronic diabetic rats, which promisingly support the use of GBE as a food supplement or an adjunct treatment for diabetics. Expand
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TLDR
The results suggest that benfotiamine suppresses oxidative stress-induced NF-kappaB-dependent inflammatory signaling leading to uveitis, and could be used as a novel therapeutic agent for the treatment of ocular inflammation, especially Uveitis. Expand
Protective effects of ginkgo biloba against acetaminophen-induced toxicity in mice
TLDR
The results implicate that AAP causes oxidative damage in hepatic tissues and Ginkgo biloba extract, by its antioxidant effects protects the tissues, and its therapeutic role as a "tissue injury-limiting agent" must be further elucidated in drug-induced oxidative damage. Expand
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TLDR
It is concluded that the probable mechanisms of EGB ameliorated inflammatory injury in TNBS-induced colitis in rats by its modulation of inflammatory mediators and antioxidation. Expand
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