The effects of Ginkgo biloba extract on lipopolysaccharide-induced inflammation in vitro and in vivo.

@article{Ilieva2004TheEO,
  title={The effects of Ginkgo biloba extract on lipopolysaccharide-induced inflammation in vitro and in vivo.},
  author={Iliyana Bozhidarova Ilieva and Kazuhiro Ohgami and Kenji Shiratori and Yoshikazu Koyama and Kazuhiko Yoshida and Satoru Kase and Hirokuni Kitamei and Yuko Takemoto and Kazunaga Yazawa and Shigeaki Ohno},
  journal={Experimental eye research},
  year={2004},
  volume={79 2},
  pages={
          181-7
        }
}
ANTI-INFLAMMATORY EFFECTS OF BIDARIA KHANDALENSE EXTRACT ON RAT ENDOTOXIN-INDUCED UVEITIS
TLDR
B Bidaria khandalense extract with high levels of polyphenol compounds has been reported to have antioxidative effects in vitro and in vivo, and the effects of BKE on endotoxin and EIU in rats suggest that BKE has a dose.
Anti-inflammatory effects of aronia extract on rat endotoxin-induced uveitis.
TLDR
The results suggest that ACE has a dose-dependent anti-ocular inflammatory effect that is due to the direct blocking of the expression of the iNOS and COX-2 enzymes and leads to the suppression of the production of NO, PGE2, and TNF-alpha.
Pharmacologyonline 2 : 825-834 ( 2011 ) Estakhr and Javdan 825 ANTI-INFLAMMATORY EFFECTS OF BIDARIA KHANDALENSE EXTRACT ON RAT ENDOTOXIN-INDUCED UVEITIS
TLDR
The aim of the present study was to determine the effects of BKE on endotoxin-induced uveitis (EIU) in rats, and the expression of iNOS and COX-2 was determined in a mouse macrophage cell line treated with BKE in vitro.
Bilobalide, a unique constituent of Ginkgo biloba, inhibits inflammatory pain in rats
TLDR
Data show that bilobalide is a potent anti-inflammatory and antihyperalgesic agent, the therapeutic effects of which are mediated in part through a central site of action, and may account for the therapeutic action of the whole extract G. biloba.
Antihyperglycemic Effect of Ginkgo biloba Extract in Streptozotocin-Induced Diabetes in Rats
TLDR
GBE possesses antihyperglycemic, antioxidant, and antihyperlipidemia activities in STZ-induced chronic diabetic rats, which promisingly support the use of GBE as a food supplement or an adjunct treatment for diabetics.
Prevention of endotoxin-induced uveitis in rats by benfotiamine, a lipophilic analogue of vitamin B1.
TLDR
The results suggest that benfotiamine suppresses oxidative stress-induced NF-kappaB-dependent inflammatory signaling leading to uveitis, and could be used as a novel therapeutic agent for the treatment of ocular inflammation, especially Uveitis.
Protective effects of ginkgo biloba against acetaminophen-induced toxicity in mice
TLDR
The results implicate that AAP causes oxidative damage in hepatic tissues and Ginkgo biloba extract, by its antioxidant effects protects the tissues, and its therapeutic role as a "tissue injury-limiting agent" must be further elucidated in drug-induced oxidative damage.
ResearchCommunication Effects of Ginkgobiloba Extract on Inflammatory Mediators (SOD, MDA, TNF-α ,N F-κBp65, IL-6) in TNBS-Induced Colitis in Rats
TLDR
It is concluded that the probable mechanisms of EGB ameliorated inflammatory injury in TNBS-induced colitis in rats by its modulation of inflammatory mediators and antioxidation.
Suppressive effect of Punica granatum on the production of tumor necrosis factor (Tnf) in BV2 microglial cells.
TLDR
Data suggest that PGME may suppress LPS-stimulated Tnf production through inhibition of Nfkappab in BV2 microglia cells.
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