The effects of GLP-1 on insulin release in young and old rats in the fasting state and during an intravenous glucose tolerance test.

Abstract

Glucose intolerance is a common feature of the aging process, and aging per se is an etiologic factor for Type II diabetes mellitus. To characterize the beta cell abnormalities that occur with aging, we looked at the serum glucose and insulin levels of six young (3-month) and six old (22-month) Wistar rats at 0, 2, 4, 7, 10, 15, 20, and 30 minutes after an… (More)

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@article{Ore1997TheEO, title={The effects of GLP-1 on insulin release in young and old rats in the fasting state and during an intravenous glucose tolerance test.}, author={K De Ore and Nigel H. Greig and Hilary Holloway and Y Wang and Riccardo Perfetti and Josephine M. Egan}, journal={The journals of gerontology. Series A, Biological sciences and medical sciences}, year={1997}, volume={52 5}, pages={B245-9} }