The effects of DISC1 risk variants on brain activation in controls, patients with bipolar disorder and patients with schizophrenia.

@article{Chakirova2011TheEO,
  title={The effects of DISC1 risk variants on brain activation in controls, patients with bipolar disorder and patients with schizophrenia.},
  author={Goultchira Chakirova and Heather C Whalley and Pippa A Thomson and William Hennah and T. William J. Moorhead and Killian A Welch and S Rashelle Giles and Jeremy Hall and Eve C. Johnstone and Stephen M Lawrie and David J. Porteous and Verity J Brown and Andrew M. McIntosh},
  journal={Psychiatry research},
  year={2011},
  volume={192 1},
  pages={20-8}
}
Three risk variants (rs1538979, rs821577, and rs821633) in the Disrupted-in-Schizophrenia-1 (DISC1) gene have previously been associated with both schizophrenia and bipolar disorder in a recent collaborative analysis of European cohorts. In this study we examined the effects of these risk variants on brain activation during functional magnetic resonance imaging (fMRI) of the Hayling Sentence Completion Task (HSCT) in healthy volunteers (n=33), patients with schizophrenia (n=20) and patients… CONTINUE READING
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The Hayling and Brixton Tests

  • P. Burgess, T. Shallice
  • Bury St. Edmunds,
  • 1997
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