The effects of 4-thujanol on chromosome aberrations, sister chromatid exchanges and micronucleus in human peripheral blood lymphocytes

@article{Kocaman2011TheEO,
  title={The effects of 4-thujanol on chromosome aberrations, sister chromatid exchanges and micronucleus in human peripheral blood lymphocytes},
  author={Ayşe Yavuz Kocaman and Eyy{\"u}p Renc{\"u}zoğulları and Mehmet Topaktaş and Erman Salih Istifli and Mehmet B{\"u}y{\"u}kleyla},
  journal={Cytotechnology},
  year={2011},
  volume={63},
  pages={493-502}
}
4-Thujanol, a bicyclic monoterpene alcohol, is present in the essential oils of many medicinal and aromatic plants. It is commonly used as a fragrance and flavouring ingredient in a lot of different products. The potential genotoxic effects of 4-thujanol on human peripheral blood lymphocytes (PBLs) were investigated in vitro by the chromosome aberrations (CAs), sister chromatid exchanges (SCEs), and micronucleus (MN) tests. The cells were treated with 13, 26 and 52 μg/mL 4-thujanol in the… CONTINUE READING