The effectiveness of electroconvulsive therapy: A literature review

@article{Read2010TheEO,
  title={The effectiveness of electroconvulsive therapy: A literature review},
  author={J. Read and R. Bentall},
  journal={Epidemiology and Psychiatric Sciences},
  year={2010},
  volume={19},
  pages={333 - 347}
}
SUMMARY Aim – To review the literature on the efficacy of electroconvulsive therapy [ECT], with a particular focus on depression, its primary target group. Methods – PsycINFO, Medline, previous reviews and meta-analyses were searched in an attempt to identify all studies comparing ECT with simulated-ECT [SECT]. Results – These placebo controlled studies show minimal support for effectiveness with either depression or ‘schizophrenia’ during the course of treatment (i.e. only for some patients… Expand
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TLDR
The quality of most SECT–ECT studies is so poor that the meta-analyses were wrong to conclude anything about efficacy, either during or beyond the treatment period, and its use should be immediately suspended. Expand
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  • Medicine
  • The British Journal of Psychiatry
  • 2020
TLDR
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TLDR
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  • Psychology, Medicine
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TLDR
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controversy. The mechanism of action remains unknown, which attracts criticism. Currently, the most widely accepted theory is that ECT alters the postsynaptic effects of central nervous systemExpand
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References

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TLDR
A systematic overview and meta-analysis of randomised controlled trials and observational studies for the efficacy and safety of electroconvulsive therapy with simulated ECT, ECT versus pharmacotherapy, and different forms of ECT for patients with depressive illness found ECT is an effective short-term treatment for depression. Expand
A Meta-Analysis of Electroconvulsive Therapy Efficacy in Depression
TLDR
Some evidence was found that psychosis predicted better response to ECT, and ECT was shown to be superior to medication and simulated ECT. Expand
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TLDR
There is some evidence to support the use of ECT for those with schizophrenia for short term relief of symptoms and limited evidence exists to suggest that combining antipsychotic drugs and ECT increases the rate and extent of clinical improvement, in the short term. Expand
Sham electroconvulsive therapy studies in depressive illness: a review of the literature and consideration of the placebo phenomenon in electroconvulsive therapy practice.
TLDR
The sham ECT literature is reviewed in detail, and the author discusses possible mechanisms by which sham-treated patients improved, and some information regarding ECT response of depressive subtypes that informs the modern ECT practitioner. Expand
Patients' perspectives on electroconvulsive therapy: systematic review
TLDR
The current statement for patients from the Royal College of Psychiatrists that over 80% of patients are satisfied with electroconvulsive therapy and that memory loss is not clinically important is unfounded. Expand
The Cognitive Effects of Electroconvulsive Therapy in Community Settings
TLDR
A prospective, naturalistic, longitudinal study of clinical and cognitive outcomes in patients with major depression treated at seven facilities in the New York City metropolitan area. Expand
Combined Use of Electroconvulsive Therapy and Antipsychotics in Schizophrenia: the Indian Evidence. A Review and a Meta-analysis
TLDR
The evidence was not conclusive because of several methodological difficulties, but it does suggest that further research is required to determine the usefulness of the ECT-antipsychotic combination in the acute treatment of schizophrenia. Expand
THE NORTHWICK PARK ELECTROCONVULSIVE THERAPY TRIAL
TLDR
In the real-ECT group memory was impaired during treatment but memory tests revealed no difference between the groups at six-month follow-up, and the therapeutic benefits of electrically induced convulsions in depression were more transient than has been claimed. Expand
Effect of ECT on mortality and clinical outcome in geriatric unipolar depression.
TLDR
Patients who received ECT were more likely to exhibit psychomotor retardation and to have had prior courses of ECT than those who did not receive ECT and to demonstrate greater clinical improvement than those treated only with pharmacotherapy. Expand
[The efficacy of ECT treatment in depression: a meta-analysis].
TLDR
ECT treatment is an efficient tool in the short-term treatment of depression, and its effect is superior to antidepressant drug treatment and thus its use may be advantageous in patients suffering from severe depression with elevated suicidal risk. Expand
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