The effective duration of analgesia after intrathecal morphine in patients without additional opioid analgesia: a randomized double-blind multicentre study on orthopaedic patients.

@article{Gehling2009TheED,
  title={The effective duration of analgesia after intrathecal morphine in patients without additional opioid analgesia: a randomized double-blind multicentre study on orthopaedic patients.},
  author={Matthias Gehling and T. L{\"u}sebrink and Peter J Kulka and Michael Tryba},
  journal={European journal of anaesthesiology},
  year={2009},
  volume={26 8},
  pages={
          683-8
        }
}
BACKGROUND AND OBJECTIVE To know whether the application of patient-controlled analgesia devices could be avoided if intrathecal morphine is given in combination with spinal anaesthesia. METHODS In a randomized, double-blind multicentre study, 188 orthopaedic patients were randomized to receive intrathecally placebo, 0.1 mg morphine or 0.2 mg morphine in addition to 15 mg bupivacaine. The primary outcome parameter was the number of patients without any additional request for opioid during a… CONTINUE READING
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Intrathecal morphine in orthopaedic surgery patients . Optimised dose in patients receiving dipyrone

M Gehling, M Tryba
Anaesthesist • 2008