The effect of volume occupancy upon the thermodynamic activity of proteins: some biochemical consequences


The thermodynamic activity of proteins in solution is substantially altered by the addition of unreactive or ‘inert’ macromolecules occupying more than a few percent of total solution volume. Approximate theoretical models of this effect have been formulated using a simplified geometrical representation of molecular shapes. These models predict that under… (More)
DOI: 10.1007/BF00673707


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