The effect of verapamil on cardiovascular and metabolic responses to exercise

  title={The effect of verapamil on cardiovascular and metabolic responses to exercise},
  author={Hans-Joachim Petri and B. Arends and Marleen A. van Baak},
  journal={European Journal of Applied Physiology and Occupational Physiology},
In a double-blind cross-over study, the effects of verapamil on the cardiovascular and metabolic changes during a progressive maximal exercise test were studied in 12 healthy volunteers. Each subject was treated with placebo and verapamil in 3 different dosages: 3×40, 3×80 and 3×120 mg · d−1 in random order. Drugs were administered for 2 days; on the 3rd day, 2 h after the last dose, a progressive exercise test until exhaustion was performed on a bicycle ergometer. No significant differences in… CONTINUE READING

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