The effect of varying impact energy on diffuse axonal injury in the rat brain: a preliminary study

@article{Kallakuri2002TheEO,
  title={The effect of varying impact energy on diffuse axonal injury in the rat brain: a preliminary study},
  author={Srinivasu Kallakuri and John M. Cavanaugh and A. Cuneyt {\"O}zaktay and Tsuneo Takebayashi},
  journal={Experimental Brain Research},
  year={2002},
  volume={148},
  pages={419-424}
}
Diffuse axonal injury (DAI) is seen as widespread damage in the white matter of brain characterized by morphological changes to axons throughout the brain and brain stem. The current study attempted to investigate the effect of increasing impact energy on the presence and severity of DAI in corpus callosum (CC). DAI was induced in adult male Sprague-Dawley rats using an injury model adapted from Marmarou et al. in 1994. A 450-g cylindrical brass weight was dropped from three different heights… CONTINUE READING

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