The experiments were conducted on the male rats of Wistar line with initial body mass of 150-180 g. The animals were exposed to a single gamma-irradiation with doses of 1.0, 5.0 and 9.0 Gy in April-May using the radiation source 60Co with dose rates of 0.001, 0.01, 0.01, 1.0 Gy/m. The vitamin E content values both in the norm and in 0.5, 1, 2, 4, 6, 8, 10, 15, 20 and 30 days after irradiation are given. The control researches were carried out simultaneously with each series of experiments on animals of appropriate age The experiment data show that dependence of vitamin E products has an wavelike character. The possible causes of the vitamin E level decrease under intake of small and high doses of gamma-irradiation are discussed. The experimental data demonstrated the different sensitivity of the vitamin E to the doses of 1.0, 5.0, 9.0 Gy radiation depending on the dose power, the changes of these parameters being kept for a long time after irradiation.