The effect of variations in vitamin C intake on the cellular immune response of guinea pigs.

@article{Fraser1980TheEO,
  title={The effect of variations in vitamin C intake on the cellular immune response of guinea pigs.},
  author={Robin C. Fraser and S. Pavlovic and C G Kurahara and Akira Murata and Nils S. Peterson and K. B. Taylor and George A. Feigen},
  journal={The American journal of clinical nutrition},
  year={1980},
  volume={33 4},
  pages={
          839-47
        }
}
The uptake of tritiated thymidine by isolated peripheral blood lymphocytes obtained from male guinea pigs immunized with bovine serum albumin was studied in animals maintained on various amounts of Vitamin C for 28 days. Animals were pair-fed on ascorbate-free diet and were supplemented intraperitoneally with 0, 25, or 250 mg Na-ascorbate per day. Scorbutic animals lost weight rapidly during the final 2 experimental weeks. Their daily food intake averaged only 4 g/day during the last week; thus… CONTINUE READING

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