The effect of variation in expression of the candidate dyslexia susceptibility gene homolog Kiaa0319 on neuronal migration and dendritic morphology in the rat.

@article{Peschansky2010TheEO,
  title={The effect of variation in expression of the candidate dyslexia susceptibility gene homolog Kiaa0319 on neuronal migration and dendritic morphology in the rat.},
  author={Veronica J Peschansky and Timothy J. Burbridge and Amy J Volz and Christopher G Fiondella and Zach Wissner-Gross and Albert M. Galaburda and Joseph J Lo Turco and Glenn D. Rosen},
  journal={Cerebral cortex},
  year={2010},
  volume={20 4},
  pages={884-97}
}
We investigated the postnatal effects of embryonic knockdown and overexpression of the candidate dyslexia gene homolog Kiaa0319. We used in utero electroporation to transfect cells in E15/16 rat neocortical ventricular zone with either 1) small hairpin RNA (shRNA) vectors targeting Kiaa0319, 2) a KIAA0319 expression construct, 3) Kiaa0319 shRNA along with… CONTINUE READING