The effect of using simethicone with or without N-acetylcysteine before gastroscopy: A meta-analysis and systemic review
@article{Li2019TheEO, title={The effect of using simethicone with or without N-acetylcysteine before gastroscopy: A meta-analysis and systemic review}, author={Yuanfa Li and Fangjuan Du and Dou Fu}, journal={Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association}, year={2019}, volume={25}, pages={218 - 228} }
Background/Aim: To assess the efficacy and safety of simethicone with or without N-acetylcysteine (NAC) as premedications before gastroscopy. Materials and Methods: We searched EMBASE, PubMed, Cochrane library and Web of Science database for randomized clinical controlled trials regarding simethicone ± NAC as oral drinking agents before gastroscopy. Statistical software RevMan5.3 was used for statistical analysis. Results: Ten randomized clinical trials that fulfilled the inclusion criteria…
10 Citations
Improving the mucosal visualization at gastroscopy: a systematic review and meta-analysis of randomized, controlled trials reporting the role of Simethicone ± N-acetylcysteine.
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- 2018
The findings of current study on 1,099 patients successfully demonstrate that the pre-procedure oral administration of Simethicone ± N-acetylcysteine improves mucosal visualization and mucosal visualize score during OGD.
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Data from this study show that premedication with simethicone and N-acetylcysteine results in significantly better endoscopic visualization of gastric mucosa, and the proposed Crema Stomach Cleaning Score could be useful for standardizing this evaluation.
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- 2022
Premedication with simethicone before upper gastrointestinal endoscopy significantly improves the quality of GMV without affecting the duration of the examination, patient satisfaction, and the rate of side effects.
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