The effect of uremia on platelet contractile force, clot elastic modulus and bleeding time in hemodialysis patients.

@article{Brophy2007TheEO,
  title={The effect of uremia on platelet contractile force, clot elastic modulus and bleeding time in hemodialysis patients.},
  author={Donald F Brophy and Erika J Martin and Sheryl L. Carr and Barry Kirschbaum and M. Eric Carr},
  journal={Thrombosis research},
  year={2007},
  volume={119 6},
  pages={723-9}
}
INTRODUCTION Uremic bleeding frequently occurs in dialysis patients. Although its mechanism is not well characterized, acquired platelet dysfunction has been implicated in its pathogenesis. Skin bleeding time has been used to characterize platelet dysfunction in this population. However, the bleeding time is prone to error. The goal of this study was to compare the bleeding time to the novel platelet function parameters platelet contractile force and clot elastic modulus as well as platelet… CONTINUE READING

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