The effect of urea on catabolite sensitive operons in Escherichia coli K 12


Low concentrations of urea specifically inhibit the expression of catabolite sensitive genes (the lactose, galactose and maltose operons and the tryptophanase gene). This inhibition depends upon growth conditions, i.e. carbon source and temperature. The main effect of urea is exerted at the level of transcription initiation. However an additional inhibitory… (More)
DOI: 10.1007/BF00337868

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