The effect of type-2-diabetes-related vascular endothelial dysfunction on skin physiology and activities of daily living.

@article{Petrofsky2011TheEO,
  title={The effect of type-2-diabetes-related vascular endothelial dysfunction on skin physiology and activities of daily living.},
  author={Jerrold Scott Petrofsky},
  journal={Journal of diabetes science and technology},
  year={2011},
  volume={5 3},
  pages={657-67}
}
A common factor contributing to organ damage in type 2 diabetes mellitus (T2DM) is impaired tissue blood flow caused by damage to vascular endothelial cells (VECs). Damage can occur even before the clinical diagnosis of diabetes. It can be caused by both a high average blood glucose concentration and/or large daily spikes in blood glucose. While much of the present literature focuses on the damage to VECs and organs from these large glucose excursions, this review will focus on the consequence… CONTINUE READING
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