The effect of two diphosphonates on the resorption of mouse calvariain vitro

Abstract

Two diphosphonates, disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP) and disodium dichloromethyle diphosphonate (Cl2MDP), inhibit cell-mediated bone resorption of mouse calvaria cultivated for 48 hoursin vitro, when the compounds are added to the medium. Cl2MDP is more effective than EHDP over the dose range 0–16 μg P/ml. Pyrophosphate and… (More)
DOI: 10.1007/BF02012561

Topics

8 Figures and Tables

Cite this paper

@article{Reynolds1972TheEO, title={The effect of two diphosphonates on the resorption of mouse calvariain vitro}, author={J. Reynolds and Cedric Minkin and D. Brian Morgan and Dr. M. A. Spycher and Herbert Andre Fleisch}, journal={Calcified Tissue Research}, year={1972}, volume={10}, pages={302-313} }