The effect of trypan blue on the development of the ferret and rat.

@article{Beck1978TheEO,
  title={The effect of trypan blue on the development of the ferret and rat.},
  author={Felix Beck and P Swidzinska and A P Gulamhusein},
  journal={Teratology},
  year={1978},
  volume={18 2},
  pages={187-91}
}
The teratogenic effects of trypan blue given to pregnant rats and ferrets at equivalent stages of embryonic development are described. In the rat the well known teratogenicity of the dye at 8.5 days of gestation and the surprising cessation of teratogenic effect at 11.5 days (20+ somites) is confirmed. In the ferret the drug is teratogenic both at 13 and 18 days of gestation though the principal abnormalities seen are different to those described in the rat. It has been suggested that the… CONTINUE READING

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