The effect of triclosan on the uterotrophic response to extended doses of ethinyl estradiol in the weanling rat.

@article{Louis2013TheEO,
  title={The effect of triclosan on the uterotrophic response to extended doses of ethinyl estradiol in the weanling rat.},
  author={Gwendolyn W Louis and Daniel R Hallinger and Tammy E Stoker},
  journal={Reproductive toxicology},
  year={2013},
  volume={36},
  pages={
          71-7
        }
}
Triclosan (TCS), an antibacterial, has been shown to be an endocrine disruptor in the rat. We reported previously that TCS potentiated the estrogenic effect of ethinyl estradiol (EE) on uterine growth in rats exposed to EE and TCS in the uterotrophic assay, whereas TCS alone had no effect. To further characterize this potentiation, we evaluated the effect of co-exposure with lower doses of EE that are comparable to the concentrations in hormone replacement regimens and began to assess the… CONTINUE READING

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