The effect of treatment with low dose ACE inhibitor and/or diuretic on coronary microvasculature in stroke-prone spontaneously hypertensive rats.

@article{Rakuan2000TheEO,
  title={The effect of treatment with low dose ACE inhibitor and/or diuretic on coronary microvasculature in stroke-prone spontaneously hypertensive rats.},
  author={Karel Raku{\vs}an and Nicholas Cicutti and Arnaud Maurin and David Guez and Pierre Schiavi},
  journal={Microvascular research},
  year={2000},
  volume={59 2},
  pages={
          243-54
        }
}
Angiotensin II is considered to have angiogenic properties. Nevertheless, several authors reported an increase in coronary capillary density after treatment with ACE inhibitors. The aim of the present study was to evaluate the effect of treatment with low doses of ACE inhibitor perindopril, low doses of the diuretic indapamide, or a combination of the two on microvascular structure in hearts from stroke-prone spontaneously hypertensive rats (SHR-sp). Young adult male SHR treated with indapamide… CONTINUE READING
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