The effect of topography of polymer surfaces on platelet adhesion.

@article{Koh2010TheEO,
  title={The effect of topography of polymer surfaces on platelet adhesion.},
  author={Li Buay Koh and Isabel Rodr{\'i}guez and Subbu S Venkatraman},
  journal={Biomaterials},
  year={2010},
  volume={31 7},
  pages={1533-45}
}
In this study, the effect of surface topography on fibrinogen and platelet adsorption was investigated. High aspect ratio surface features, in the submicron to nanometer range, were constructed on the poly- (lactic-co-glycolic-acid) (PLGA) films. The topographic surfaces were fabricated by solvent-mediated polymer casting on a master template. Fibrinogen adsorption and platelets adhesion on these topographic surfaces were quantified by enzyme linked immunosorbent assay (ELISA) and lactate… CONTINUE READING