The effect of tolerance to noninherited maternal HLA antigens on the survival of renal transplants from sibling donors.

@article{Burlingham1998TheEO,
  title={The effect of tolerance to noninherited maternal HLA antigens on the survival of renal transplants from sibling donors.},
  author={William J. Burlingham and Alan P. Grailer and Dennis M. Heisey and Franz H J Claas and Douglas Everett Norman and Thalchallour Mohanakumar and Daniel C. Brennan and Hans J W de Fijter and Teun van Gelder and John D. Pirsch and Hans W Sollinger and Michael A. Bean},
  journal={The New England journal of medicine},
  year={1998},
  volume={339 23},
  pages={1657-64}
}
BACKGROUND During pregnancy and nursing, a baby's developing immune system is intimately exposed to the mother's antigens. To determine whether this exposure is of clinical benefit to patients who later receive an allograft as an adult, we analyzed the outcome of primary renal transplantations from sibling donors. METHODS We retrospectively studied graft survival and rejection episodes in 205 patients who had received renal transplants at nine centers between 1966 and 1996 from sibling donors… CONTINUE READING

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