The effect of thymoquinone, an active component of Nigella sativa, on isoproterenol induced myocardial injury.

@article{Randhawa2013TheEO,
  title={The effect of thymoquinone, an active component of Nigella sativa, on isoproterenol induced myocardial injury.},
  author={Mohammad Akram Randhawa and Mastour Safar Alghamdi and Subir Kumar Maulik},
  journal={Pakistan journal of pharmaceutical sciences},
  year={2013},
  volume={26 6},
  pages={
          1215-9
        }
}
Myocardial injury constitutes a major cause of morbidity and mortality in humans. Present study aimed to investigate protective role of thymoquinone, which is an active principle of Nigella sativa (N. sativa) seed (Commonly called as black seed), in isoproterenol induced myocardial injury, a classical example of excess catecholamines related coronary insufficiency and stress cardiomyopathy. Thymoquinone, in olive oil, was administered orally (12.5, 25 and 50mg/kg) to three groups of Wistar… CONTINUE READING
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