The effect of therapeutic hypothermia on the expression of inflammatory response genes following moderate traumatic brain injury in the rat.


Traumatic brain injury (TBI) initiates a cascade of cellular and molecular responses including both pro- and anti-inflammatory. Although post-traumatic hypothermia has been shown to improve outcome in various models of brain injury, the underlying mechanisms responsible for these effects have not been clarified. In this study, inflammation cDNA arrays and… (More)


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