The effect of the fiber components cellulose and lignin on experimental colon neoplasia.

@article{Sloan1993TheEO,
  title={The effect of the fiber components cellulose and lignin on experimental colon neoplasia.},
  author={David A. Sloan and David Fleiszer and Gill Richards and Dennis Murray and Rea A Brown},
  journal={Journal of surgical oncology},
  year={1993},
  volume={52 2},
  pages={77-82}
}
Sixty Sprague-Dawley rats were pair-fed one of three nutritionally identical diets. One diet contained "low-fiber" (3.8% crude fiber); the others contained "high fiber" (28.7% crude fiber) composed of either cellulose or lignin. Although both "high fiber" diets had similar stool bulking effects, only the cellulose diet was associated with a reduction in 1,2-dimethylhydrazine (DMH)-induced colon neoplasms. The cellulose diet was also associated with distinct changes in the gut bacterial profile… CONTINUE READING