The effect of the antiprogestin mifepristone (RU 486) on maturation and in-vitro fertilization of human oocytes.

Abstract

The effect of RU 486 (mifepristone), a potent antiprogestin, on the in-vitro fertilization of human oocytes was investigated. In 40 normal volunteer women requesting laparoscopic sterilization, follicle aspiration for oocyte recovery was attempted 34 h after the injection of 5000 i.u. human chorionic gonadotrophin (hCG). Twenty women were allocated to… (More)

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@article{Messinis1988TheEO, title={The effect of the antiprogestin mifepristone (RU 486) on maturation and in-vitro fertilization of human oocytes.}, author={I. E. Messinis and A. Templeton}, journal={British journal of obstetrics and gynaecology}, year={1988}, volume={95 6}, pages={592-5} }