The effect of the anti-estrogen tamoxifen on cardiovascular risk factors in normal postmenopausal women.

@article{Grey1995TheEO,
  title={The effect of the anti-estrogen tamoxifen on cardiovascular risk factors in normal postmenopausal women.},
  author={A. Grey and J. Stapleton and M. Evans and I. Reid},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1995},
  volume={80 11},
  pages={
          3191-5
        }
}
There is growing interest in the use of anti-estrogens as agents of disease prevention. Studies of women with breast cancer suggest that the synthetic anti-estrogen tamoxifen may reduce the incidence of cardiovascular disease, but the effects of this agent on cardiovascular risk factors in healthy women have not been studied. We have performed a two-year, randomized, placebo-controlled trial to assess the effects of tamoxifen 20 mg/day on serum lipids, fibrinogen, and body composition in 57… Expand
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