The effect of temperature on the lateral diffusion of plasma membrane proteins.

@article{Edidin1977TheEO,
  title={The effect of temperature on the lateral diffusion of plasma membrane proteins.},
  author={Michael A Edidin and V A Petit},
  journal={Ciba Foundation symposium},
  year={1977},
  volume={52},
  pages={
          155-74
        }
}
Cooling is expected to gradually reduce the lateral diffusion of membrane proteins, at a rate predicted from the changes in viscosity and order observed on cooling defined lipids and lipid mixtures. However, a continuous change in diffusion rate with falling temperature is not observed in mammalian cells. Rather, on cooling below around 20 degrees C, protein diffusion rates are found to increase, reaching a new maximum at 15 degrees C. This anomaly in diffusion rate could result in irreversible… CONTINUE READING