The effect of streptokinase on intramyocardial hemorrhage, infarct size, and the no-reflow phenomenon during coronary reperfusion.

@article{Kloner1984TheEO,
  title={The effect of streptokinase on intramyocardial hemorrhage, infarct size, and the no-reflow phenomenon during coronary reperfusion.},
  author={Robert A. Kloner and Kevin J. Alker},
  journal={Circulation},
  year={1984},
  volume={70 3},
  pages={513-21}
}
The purpose of this study was to determine whether streptokinase exacerbates intramyocardial hemorrhage during coronary reperfusion, has any intrinsic effect on myocardial infarct size other than its ability to lyse proximal thrombi in coronary arteries, and can abolish the no-reflow phenomenon. Anesthetized open-chest dogs underwent coronary occlusion for 3 hr followed by 3 hr of reperfusion. Area of infarct was assessed by tetrazolium staining, anatomic zone of no-reflow by injection of the… CONTINUE READING
39 Citations
35 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 39 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Udell JR , Sobel BE , Williamson JR : External detection of early microvascular dysfunction after no - reflow ischemia followed by reperfusion in isolated rabbit hearts

  • RG Tilton, KB Larson
  • Circ Res
  • 1983

Similar Papers

Loading similar papers…