The effect of spontaneous breathing on systemic interleukin-6 during ventilator weaning.


During the weaning process, spontaneous breathing trials (SBTs) involve cardiopulmonary stress for ventilated patients. As interleukin (IL)-6 is a major modulator of the stress response, we hypothesised that systemic IL-6 increases during a SBT and that this increase is more evident in SBT failure. 49 SBTs of 30-min duration were performed on different… (More)
DOI: 10.1183/09031936.00037511