The effect of space radiation on the induction of chromosome damage.

  title={The effect of space radiation on the induction of chromosome damage.},
  author={Kerry A. George and Honglu Wu and Veronica Willingham and Francis A. Cucinotta},
  journal={Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics},
  volume={17 Suppl 1},
To obtain information on the cytogenetic damage caused by space radiation, chromosome exchanges in lymphocytes from crewmembers of long-term Mir missions, and a shorter duration shuttle mission, were examined using fluorescence in situ hybridization. A significant increase in chromosomal aberrations was observed after the long duration flights. The ratio of aberrations identified as complex was higher post-flight for some crewmembers, which is thought to be an indication of exposure to high-LET… CONTINUE READING
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