The effect of serotonin 1A receptor polymorphism on the cognitive function of premenstrual dysphoric disorder

@article{Yen2013TheEO,
  title={The effect of serotonin 1A receptor polymorphism on the cognitive function of premenstrual dysphoric disorder},
  author={J. Yen and H. Tu and C. Chen and C. Yen and C. Long and C. Ko},
  journal={European Archives of Psychiatry and Clinical Neuroscience},
  year={2013},
  volume={264},
  pages={729-739}
}
  • J. Yen, H. Tu, +3 authors C. Ko
  • Published 2013
  • Psychology, Medicine
  • European Archives of Psychiatry and Clinical Neuroscience
Estrogen and serotonin play vital roles in the mechanism of premenstrual dysphoric disorder (PMDD). Cognitive deficit in the premenstrual phase contributes to impaired life function among women with PMDD. The aim of this study was to evaluate the difficulties in cognitive control and working memory (WM) in PMDD and to explore the effects of gonadotropic hormone and polymorphism of serotonin 1A receptor (HTR1A; rs6295) on cognitive deficit in PMDD. Women with PMDD completed diagnostic… Expand
Cognition, The Menstrual Cycle, and Premenstrual Disorders: A Review
TLDR
There is a lack of consistent findings regarding cognitive functioning across the menstrual cycle, and most studies focused on changes in levels of blood estrogen, and neglected to explore the role of other hormones, such as progesterone, on cognitive functioning. Expand
Premenstrual appetite and emotional responses to foods among women with premenstrual dysphoric disorder
TLDR
Targeted assessment of increased late-luteal appetites for HS foods may facilitate clinical interventions in women with premenstrual dysphoric disorder, and there were significant correlations between emotional responses to and desire to eat HS foods. Expand
Association between Generalized Anxiety Disorder and Premenstrual Dysphoric Disorder in a Diagnostic Interviewing Study
TLDR
Women with GAD were more likely to have Premenstrual dysphoric disorder and their anxiety, depression, and irritability should be intervened not only in the luteal phase, but also in the follicular phase. Expand
Subtle persistent working memory and selective attention deficits in women with premenstrual syndrome
TLDR
Evidence of persistent, subtle working memory and selective attention difficulties in those with moderate to severe PMS during the follicular phase of the menstrual cycle is provided. Expand
Estrogen levels, emotion regulation, and emotional symptoms of women with premenstrual dysphoric disorder: The moderating effect of estrogen receptor 1α polymorphism
TLDR
The association between estrogen and anxiety in PMDD is demonstrated, supporting the claim that women with PMDD differ in their responses to normal estrogen levels, and among the G carriers of ESR &agr;‐Xbal polymorphism. Expand
Reproductive Affective Disorders: a Review of the Genetic Evidence for Premenstrual Dysphoric Disorder and Postpartum Depression
TLDR
Evidence is stronger for the genetic basis for PPD, with positive associations found in family studies and in several genes associated with major depression as well as genes involved in estrogen signaling but only when PPD onset is shortly after delivery. Expand
Insomnia, Inattention and Fatigue Symptoms of Women with Premenstrual Dysphoric Disorder
TLDR
These symptoms are correlated with PMDD symptoms severity and functional impairment, and as such, they should be evaluated, and interventions should be employed in the late luteal phase of women with PM DD. Expand
New aspects of cognition domains and psychopathological measures in psychiatry
TLDR
The authors found confirmation of the hypothesized applicability of their PANSS structure which well fit the data at admission and discharge, showing positive symptoms to respond better to treatment than all other symptom dimensions albeit more pronounced in the schizoaffective and bipolar groups. Expand
Interaction effect between 5-HTTLPR and HTR1A rs6295 polymorphisms on the frontoparietal network
TLDR
A significant interaction effect of 5-HTTLPR and rs6295 on the connectivity within the right frontoparietal network, specifically in the middle frontal gyrus and inferior parietal lobule is found. Expand
The late-luteal leptin level, caloric intake and eating behaviors among women with premenstrual dysphoric disorder
TLDR
A decline in the leptin level is associated with late-luteal overeating among normal-weight women with premenstrual dysphoric disorder and hyperleptinemia and a high sweet caloric intake of overweight women with PMDD should be monitored and addressed in order to attenuate the risk of leptin resistance. Expand
...
1
2
3
...

References

SHOWING 1-10 OF 50 REFERENCES
Cognitive Functioning in Premenstrual Syndrome
TLDR
The authors' sample of women with PMS failed to demonstrate objective evidence of diminished cognitive performance, despite subjective feelings of inadequacy. Expand
A PET study of 5-HT1A receptors at different phases of the menstrual cycle in women with premenstrual dysphoria
TLDR
New support is provided, in vivo, for a serotonergic dysregulation in women with PMDD by positron emission tomography and [carbonyl-(11)C]WAY-100635 used to examine serotonin 5-HT(1A) receptors in a control group of women and in a group ofWomen with PM DD. Expand
Mood, neuropsychological function and cognitions in premenstrual dysphoric disorder.
TLDR
The results show that the BDI is sensitive to the mood fluctuations of PMDD patients, and an impairment in working memory was found although this is a general menstrual cycle effect. Expand
Cognitive flexibility, reaction time, and attention in women with premenstrual dysphoric disorder.
  • M. Morgan, A. Rapkin
  • Medicine
  • The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia
  • 2002
TLDR
Cognitive functioning in the late-luteal phase was not compromised in either group, in spite of subjective reports from the PDD group, and the findings suggest that complaints of cognitive dysfunction may be mediated by altered perceptions and sociocultural expectations rather than by identifiable cognitive deficits. Expand
Pathophysiology of premenstrual syndrome and premenstrual dysphoric disorder
TLDR
Brain imaging studies have begun to shed light on the complex brain circuitry underlying affect and behaviour and may help to explicate the intricate neurophysiological foundation of the syndrome. Expand
The effect of premenstrual dysphoric disorder and menstrual cycle phase on brain activity during response inhibition.
TLDR
During response inhibition women with PMDD have reduced activity in areas associated with attention and motor function which is unrelated to menstrual cycle phase, which is relevant for the understanding of how ovarian steroids influence mood symptoms in women. Expand
Working memory deficit in premenstrual dysphoric disorder and its associations with difficulty in concentrating and irritability.
TLDR
Working memory deficit is aggravated in the luteal phase among women with premenstrual dysphoric disorder and Appropriate interventions are needed to prevent negative consequences of working memory deficit. Expand
Effect of menstrual cycle phase on neuroendocrine and behavioral responses to the serotonin agonist m-chlorophenylpiperazine in women with premenstrual syndrome and controls.
TLDR
The findings implicate the serotonin system as a modulating (not causal) factor in PMS, and provide evidence for the acute efficacy of m-CPP in the treatment of PMS. Expand
Memory function in women with premenstrual complaints and the effect of serotonergic stimulation by acute administration of an alpha-lactalbumin protein
TLDR
It was found that both short-term and long-term memory for words and abstract figures were mildly impaired in the premenstrual phase, suggesting that serotonergic hypofunction may play a role in pre menstrual memory decline, butserotonergic mechanisms cannot fully account for observed cognitive changes in the prior phase. Expand
Selective serotonin reuptake inhibitors for premenstrual syndrome.
TLDR
SSRIs were found to be highly effective in treating premenstrual symptoms and there was no significant difference between trials funded by pharmaceutical companies and those independently funded. Expand
...
1
2
3
4
5
...