The effect of sera from women with systemic lupus erythematosus and/or antiphospholipid syndrome on rat embryos in culture.

@article{Ornoy1998TheEO,
  title={The effect of sera from women with systemic lupus erythematosus and/or antiphospholipid syndrome on rat embryos in culture.},
  author={Asher Ornoy and Sarah Yacobi and Shalom Avraham and Zeev Blumenfeld},
  journal={Reproductive toxicology},
  year={1998},
  volume={12 2},
  pages={185-91}
}
Women with systemic lupus erythematosus (SLE) with or without antiphospholipid antibodies (APLA) suffer from a high rate of recurrent abortions perhaps as a result of specific antibodies that may damage the conceptus. We studied the effects of sera from women with SLE--with or without--APLA and recurrent abortions on 10.5-d-old rat embryos in culture. This was compared to the results of culture on sera from control women and on rat sera. In addition, we studied sera from women with SLE with or… CONTINUE READING