The effect of secretin on glucose-stimulated insulin secretion in man.

@article{Shima1974TheEO,
  title={The effect of secretin on glucose-stimulated insulin secretion in man.},
  author={K. Shima and S. Tarui},
  journal={Endocrinologia japonica},
  year={1974},
  volume={21 1},
  pages={
          13-8
        }
}
The effect of physiological dose of purified secretin on glucose-stimulated insulin secretion was studied in healthy volunteers during a continuous infusion of glucose. The intravenous injection of ten unit of secretin during the infusion of glucose caused a greater rise in plasma insulin level and a more marked decrease in blood glucose concentration than either the infusion of glucose or secretin alone did, resulting in a significant increase in the insulinogenic index. One unit of secretin… Expand
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