The effect of salivary gland extract of Lucilia sericata maggots on human dermal fibroblast proliferation within collagen/hyaluronan membrane in vitro: transmission electron microscopy study.

@article{Polakoviov2015TheEO,
  title={The effect of salivary gland extract of Lucilia sericata maggots on human dermal fibroblast proliferation within collagen/hyaluronan membrane in vitro: transmission electron microscopy study.},
  author={Simona Polakovi{\vc}ov{\'a} and {\vS}tefan Pol{\'a}k and Marcela Kuniakov{\'a} and Marek {\vC}ambal and M{\'a}ria {\vC}aplovi{\vc}ov{\'a} and Milan Koz{\'a}nek and L'ubo{\vs} Dani{\vs}ovi{\vc} and Martin Kop{\'a}ni},
  journal={Advances in skin & wound care},
  year={2015},
  volume={28 5},
  pages={221-6}
}
BACKGROUND Lucilia sericata maggots are applied to chronic wounds to aid healing when conventional treatments have failed. After their application into a necrotic wound, they potentially influence wound healing with a combination of specific proteinases that are involved in the remodeling of extracellular matrix. These proteases cause changes in fibroblast adhesion and spread upon extracellular matrix protein surfaces, affecting integrity of the protein surfaces-especially fibronectin-while… CONTINUE READING
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