The effect of safranal, a constituent of Crocus sativus (saffron), on tracheal responsiveness, serum levels of cytokines, total NO and nitrite in sensitized guinea pigs.

@article{Boskabady2014TheEO,
  title={The effect of safranal, a constituent of Crocus sativus (saffron), on tracheal responsiveness, serum levels of cytokines, total NO and nitrite in sensitized guinea pigs.},
  author={Mohammad Hossein Boskabady and Goltaj Byrami and Azadeh Feizpour},
  journal={Pharmacological reports : PR},
  year={2014},
  volume={66 1},
  pages={
          56-61
        }
}
BACKGROUND The effect of safranal (one of the constituents of Crocus sativus) on ovalbumin (OVA) sensitized guinea pigs was examined. METHODS One group of sensitized guinea pigs were given drinking water alone (group S), three groups drinking water containing three concentrations of safranal and one group contain dexamethasone (S + D). Tracheal responses (TR) of the animals to methacholine as effective concentration causing 50% of maximum response (EC(50) M), TR to 0.1% OVA, relative to… CONTINUE READING

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