The effect of sa 97, perphenazine, and hydroxyzine on epinephrine-induced cardiac arrhythmias during methoxyflurane anaesthesia in dogs

@article{Dobkin1962TheEO,
  title={The effect of sa 97, perphenazine, and hydroxyzine on epinephrine-induced cardiac arrhythmias during methoxyflurane anaesthesia in dogs},
  author={A. Dobkin},
  journal={Canadian Anaesthetists’ Society Journal},
  year={1962},
  volume={9},
  pages={36-41}
}
  • A. Dobkin
  • Published 1962
  • Medicine
  • Canadian Anaesthetists’ Society Journal
  • Summary and ConclusionsForty-one aeute experiments were done on 11 mongrel dogs after 25 minutes of 1 per cent methoxyflurane-oxygen anaesthesia to determine the severity of cardiac arrhythmias produced by an epinephrine challenge and to evaluate the efficacy of SA 97 (an antihistaminic) as a protectant. Perphenazine and hydroxyzine were also used as a comparison with SA 97. Pulmonary ventilation was augmented during anaesthesia to eliminate hypoxia and hypercarbia during the experiments. The… CONTINUE READING
    Methoxyflurane and Teflurane
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