The effect of rs1076560 (DRD2) and rs4680 (COMT) on tardive dyskinesia and cognition in schizophrenia subjects

  title={The effect of rs1076560 (DRD2) and rs4680 (COMT) on tardive dyskinesia and cognition in schizophrenia subjects},
  author={T. J. Punchaichira and Prachi Kukshal and T. Bhatia and S. Deshpande and B. Thelma},
  journal={Psychiatric Genetics},
  pages={125 - 135}
  • T. J. Punchaichira, Prachi Kukshal, +2 authors B. Thelma
  • Published 2020
  • Medicine
  • Psychiatric Genetics
  • Supplemental Digital Content is available in the text. Objective The aim of the study is to test the association of a functional variant each in DRD2 and COMT genes with schizophrenia and its endophenotypes. Basic methods Effect of two functional variants rs1076560 in DRD2 and rs4680 in COMT on (1) schizophrenia (502 cases, 448 controls) diagnosed by Diagnostic and Statistical Manual of Mental Disorders-IV criteria and in subsets with (2) tardive dyskinesia (80 positive, 103 negative), assessed… CONTINUE READING


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