The effect of rexflavone (Sophorae Fructus Extract) on menopausal symptoms in postmenopausal women: A randomized double-blind placebo controlled clinical trial

@article{Lee2010TheEO,
  title={The effect of rexflavone (Sophorae Fructus Extract) on menopausal symptoms in postmenopausal women: A randomized double-blind placebo controlled clinical trial},
  author={Jeongrai Lee and Kuk Whan Kim and Hyun-Kyu Kim and Soowan Chae and Jae-chul Jung and Suk Hyung Kwon and Chul Hee Rheu},
  journal={Archives of Pharmacal Research},
  year={2010},
  volume={33},
  pages={523-530}
}
To observe the protective effect of orally administrated Rexflavone (Sophorae fructus extract) for the postmenopausal symptoms, a randomized double-blind placebo controlled clinical trial was designed. Rexflavone significantly improved 11 menopausal symptoms including hot flash, which was evaluated by the modified Kupperman Index (KI), while hormone level and lipid profile were little changed by consumption. Rexflavone group significantly decreased KI score (−14.91 ± 8.79) compared to placebo… 
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